Study of the morphological relationship existent in the Canary Island honeybee (Apis mellifera L.)

he genetic origin of the honey bees (Apis mellifera) that lives in the Canary Island is ignored. It has been speculated with the possibility that the Guanches, first island inhabitant with African origin, brought with them native bees from the continent. It is known that the first Spanish colonist transport beehives from the Iberian Peninsula, and the quality of the canary honey allowed that in the XVI century it was exported in big quantities toward Europe. This paper evaluates morphological traits in samples of honeybee workers coming from apiaries located in five islands of the archipelago. A total of 27 morphological variables was taken of each insect. The discriminant analyses carried out, using as classificatory variable the beehive of origin of the work bees, indicate that significant differences exist among the groups. Four morphological groups were identified. One of them includes the bees coming from Gran Canaria and Hierro, between this group and the one formed by the workers coming from La Gomera is located the one from Tenerife, and the one from La Palma forms an independent group. The possible relationship of these bees was estimated with another discriminant analysis that included data coming from samples of the south of Spain (A. mellifera iberica) and north of Africa (A. mellifera intermissa)

Effect of chemical structure on the sonochemical degradation of perfluoroalkyl and polyfluoroalkyl substances (PFASs)

Perfluoroalkyl surfactants include chemicals characterized by a fully fluorinated carbon chain (hydrophobic and oleophobic tail) bound to a hydrophilic head (a carboxyl or sulfonic group). These compounds are toxic and highly resistant to chemical/biological attack, and some are known to be bio-accumulative. This study investigates the sonochemical degradation at 500 kHz of different carboxylic and sulfonic perfluoroalkyl and polyfluoroalkyl substances (PFASs, 1.7 mM total organic fluorine) to assess the effect of chain length, functional head group, and substituents (–CH2–CH2– moiety and ether group) on the degradation rate. Under these conditions, the rates of defluorination determined for two widely used perfluoroalkyl substances, perfluorooctanesulfonate (PFOS) and perfluorooctanoic acid (PFOA), were 3.5 to 3.7 μM F− min−1, respectively. The degradation rate of perfluoroalkyl sulfonates decreased with the perfluorocarbon chain length as indicated by the 1.3 and 1.9-fold lower defluorination rates for perfluorohexane- and perfluorobutane sulfonate than that of PFOS. A similar trend was observed during the sonolysis of perfluoroalkyl carboxylate analogs with 6, 5 or 3 carbon atoms which had 1.1-, 1.8-, and 2.3-fold lower defluorination rates, respectively, than that of PFOA. Furthermore, perfluoroalkyl compounds appeared more amenable to sonolysis than the polyfluoroalkyl analogues with the same number of C atoms (defluorination rate of PFOS/6 : 2 fluorotelomer sulfonate ≈ 2.3). The results demonstrate that sonolysis is a promising approach to treat PFASs in aqueous streams. Furthermore, they underscore that the chemical structure of PFASs has a marked effect on the rate at which they undergo sonochemical degradation

Modeling skull-face anatomical/morphological correspondence for craniofacial superimposition-based identification

Craniofacial superimposition (CFS) is a forensic identification technique which studies the anatomical and morphological correspondence between a skull and a face. It involves the process of overlaying a variable number of facial images with the skull. This technique has great potential since nowadays the wide majority of the people have photographs where their faces are clearly visible. In addition, the skull is a bone that hardly degrades under the effect of fire, humidity, temperature changes, etc. Three consecutive stages for the CFS process have been distinguished: the acquisition and processing of the materials; the skull-face overlay; and the decision making. This final stage consists of determining the degree of support for a match based on the previous overlays. The final decision is guided by different criteria depending on the anatomical relations between the skull and the face. In previous approaches, we proposed a framework for automating this stage at different levels taking into consideration all the information and uncertainty sources involved. In this study, we model new anatomical skull-face regions and we tackle the last level of the hierarchical decision support system. For the first time, we present a complete system which provides a final degree of craniofacial correspondence. Furthermore, we validate our system as an automatic identification tool analyzing its capabilities in closed (known information or a potential list of those involved) and open lists (little or no idea at first who may be involved) and comparing its performance with the manual results achieved by experts, obtaining a remarkable performance. The proposed system has been demonstrated to be valid for sortlisting a given data set of initial candidates (in 62,5% of the cases the positive one is ranked in the first position) and to serve as an exclusion method (97,4% and 96% of true negatives in training and test, respectively)

Silica Inverse Opal Nanostructured Sensors for Enhanced Immunodetection of Extracellular Vesicles by Quartz Crystal Microbalance with Dissipation Monitoring

Extracellular vesicles (EVs) are nanosized circulating assemblies that contain biomarkers considered promising for early diagnosis within neurology, cardiology, and oncology. Recently, acoustic wave biosensors, in particular based on quartz crystal microbalance with dissipation monitoring (QCM-D), have emerged as a sensitive, label-free, and selective EV characterization platform. A rational approach to further improving sensing detection limits relies on the nanostructuration of the sensor surfaces. To this end, inorganic inverse opals (IOs) derived from colloidal self-assembly present a highly tunable and scalable nanoarchitecture of suitable feature sizes and surface chemistry. This work systematically investigates their use in two-dimensional (2D) and three-dimensional (3D) for enhanced QCM-D EV detection. Precise tuning of the architecture parameters delivered improvements in detection performance to sensitivities as low as 6.24 × 107 particles/mL. Our findings emphasize that attempts to enhance acoustic immunosensing via increasing the surface area by 3D nanostructuration need to be carefully analyzed in order to exclude solvent and artifact entrapment effects. Moreover, the use of 2D nanostructured electrodes to compartmentalize analyte anchoring presents a particularly promising design principle

Solution of the Bosonic and Algebraic Hamiltonians by using AIM

We apply the notion of asymptotic iteration method (AIM) to determine eigenvalues of the bosonic Hamiltonians that include a wide class of quantum optical models. We consider solutions of the Hamiltonians, which are even polynomials of the fourth order with the respect to Boson operators. We also demonstrate applicability of the method for obtaining eigenvalues of the simple Lie algebraic structures. Eigenvalues of the multi-boson Hamiltonians have been obtained by transforming in the form of the single boson Hamiltonian in the framework of AIM

Current trends in research, development and production of prophylactic vaccines : Report of Vaccipharma 2015 Congress

On June 14-19, 2015, the IUPHAR Section of Immunopharmacology and the Cuban Society of Pharmacology, together with the Latin- American Association of Pharmacology (ALF), Finlay Vaccine Institute and other prestigious Cuban scientific institutions, organized the Congress VACCIPHARMA 2015 (3rd International Congress on Pharmacology of Vaccines), held as part of the First International Convention IMMUNOPHARMACOLOGY–VACCIPHARMA 2015 (Meliá Marina Varadero Hotel, in Varadero beach, Cuba) VACCIPHARMA 2015 was organised into two large Workshops, addressing topics related to the research, development, clinical evaluation, production and quality control of Therapeutic and Prophylactic Vaccines, respectively. At the same time the Workshop on Prophylactic Vaccines was integrated by several Symposiums, focused on meningococcal, pneumococcal, enteric, tuberculosis and pertussis vaccines. About 250 delegates, including 100 international researchers from 15 countries, attended this meeting. The Congress had a remarkable Opening Session, with a Key Lecture given by the outstanding scientist Professor Dr. Shiv Pillai (United States of America), who talked about the changing views in the field of the immunology of vaccination and the challenges ahead. The aim of this review is to give an overview of the main topics discussed in the Prophylactic Vaccines Workshop, not as a complete narration of the events, but to provide an update of the latest state of the art and methodologies being applied to prophylactic vaccines with an expert commentary on the invited speakers